Job Description

Adcock Ingram Holdings Limited and its Subsidiaries ("we", "us") is committed to protecting and respecting your privacy. Our Privacy Notice sets out the basis on which personal information collected inter alia from you, social media, recruitment agencies and our website, will be processed by us. The Privacy notice is available on our website www.adcock.co.za.



One of the conditions under the Protection of Personal Information Act 4 of 2013 (POPIA) provides that candidates have the right to be informed about the collection and use of their personal information,



In the course of your application: we may


collect personal information that may be used to identify potential professional opportunities other than the job you have applied for but of which we think might be of interest to you. use your Personal Information to confirm references or background checks you have provided us. request your consent to participate in aptitude tests or recruitment assessments.

We also use your personal information to respond to your inquiries, to verify your information and to share information with you.



Your personal information will be securely stored by the Human Capital Department and it will be retained for a period of up to 12 months as of the closure of the application procedure if your application is unsuccessful, and in case of a successful application and you are hired, your data will be transferred to your personal employee file.



By applying for this position, you consent to us processing your personal information.



We reserve the right to make an appointment. If you have not heard from us within 30 (thirty) days of the closing date, please accept that your application was unsuccessful. Correspondence will be entered into only with shortlisted candidates.

Key Job Output

Legal compliance to SAHPRA/PICs, cGMP requirements and Pharmacy Council requirements.

To ensure that all validation related audit points identified during internal and external audits are closed timeously. To ensure that new and updated Guidelines and Policies from SAHPRA and other Regulatory bodies related to pharmaceutical industry are used at all times when developing internal documentation.

Qualifications and Validations

Compiling and updating a Validation Master Plan (VMP) and relevant Validation Plans (VPs). Ensuring the qualification of all facilities and utilities areas as per Validation Schedule. Standardising validation approach ensuring consistency of application in accordance with agreed timelines and schedules. Ensure qualification of all equipment and validation of processes as per the equipment train and product portfolio. Ensuring the requalification and/or periodic reviews of all qualified equipment and utilities as per Validation Schedule. Comprehension of sterile manufacturing concept and associated processes such as the media fill, media hold, dirty and clean hold time studies. Determining test requirements and detection limits for validation samples to the Laboratory. Coordinating site calibration activities for all critical instruments and equipment. Samples Analyzed and report all non-conformances and failures. Providing recommendations and guidance on changes related to manufacturing process, equipment and procedures. Performing cleaning validations and ensure that the cleaning validation matrix for all departments is maintained, protocols and reports are prepared in time. Proficiency in computerised system validation and application of relevant guidelines such as 21 CFR 11 Part 11, PIC/S Annex 11, GAMP 4, GAMP 5 etc. Compiling and updating departmental SOPs, protocols and reports. Proficient in the use of structured problem-solving tools and Quality Management System such as RCA (Root Cause Analysis), FMEA's (Failure Mode effects analysis), Change Control, Deviation, Corrective and Preventative Actions etc. Proficiency in project management and use of relevant tracking tools. Managing budget, operating and capital expenses.

Self-development

Study new guidelines and policies from SAHPRA/PICS to keep abreast with developments and changes with regards to legal aspects and regulatory requirement pertaining to pharmaceutical, product manufacturing. Identify and communicate any skills/training requirements to help execute tasks efficiently.

Time Management and Self Discipline

To ensure time keeping at all times To ensure that tasks allocated to individuals are performed and presented in time as scheduled


Degree within Natural Sciences or Engineering * Minimum of 5 years in pharmaceutical validation experience of which 2 years must be as a Validation Manager.