Job Description

Job Summary
A leading, award-winning global research organisation based at the Nelson Mandela School of Medicine in Durban is seeking to appoint a Junior Scientist to join its high-impact biomedical research team.
With multiple clinical research sites across KwaZulu-Natal, the organisation conducts globally relevant and locally responsive studies in HIV, Tuberculosis (TB), and COVID-19, contributing to advancements in vaccine development, pathogenesis, prevention, and treatment.
Position Summary
This role is ideal for a scientist with strong expertise in flow cytometry and cell sorting. The successful candidate will contribute to innovative clinical trial-linked immunology research, gain exposure to advanced methodologies, and receive structured mentorship to support a career in independent research.
Minimum Requirements

• Master's or PhD in Biomedical Sciences (completed within the last 2 years).
• Demonstrated expertise in:
• Flow cytometry (e.g., multicolour/spectral panel design, sample staining, and data acquisition).
• Cell sorting (bulk and single-cell applications).
• Proficiency in using relevant instruments and software, suc as:
• BD FACSCanto, FACSAria, FlowJo.
• Experience in mucosal immunology or microbiome research.
• Proven record of at least one peer-reviewed scientific publication.
• Advantageous:
• Experience with microscopy (confocal, epifluorescence, live imaging).
• Skills in image analysis

Key Competencies

• Exceptional attention to detail and analytical skills.
• Ability to manage and prioritise multiple projects effectively.
• Adaptable and calm under pressure in a fast-paced research environment.
• Capable of both independent work and team collaboration across institutions.
• Strong verbal and written communication skills.

Key Responsibilities

• Lead and implement cytometry-based projects, from sample preparation to data acquisition and high-purity cell sorting.
• Integrate cytometry workflows with downstream applications, such as:

• Transcriptomics
• Single-cell RNA sequencing
• Functional assays
• Contribute to microscopy-based imaging projects, as needed.
• Develop and maintain Standard Operating Procedures (SOPs), ensuring quality assurance and control in laboratory workflows.
• Analyse and interpret experimental data; prepare and submit manuscripts to peer-reviewed journals.
• Support grant proposals, scientific reporting, and strategic research initiatives.

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