Job Description

Description:
Africa Health Research Institute (AHRI) invites applications for a PhD training position within its basic and translational science unit, based in the Ndung'u laboratory.
Overview of Duties:
Full funding is available to support a doctoral student for 36 months effective immediately. The student will be supported to develop a proposal investigating HIV coreceptor usage and cellular tropism in a longitudinal acute infection cohort. The project will characterize coreceptor usage in transmitted/founder, reservoir-derived, and rebound viruses from individuals living with HIV-1 clade C. Analyses will include genotypic assessments, cell line-based assays, and cellular tropism studies using primary T cells and monocyte-derived macrophages. The goal of this work is to define the determinants of coreceptor usage and cellular tropism across different stages of infection and viral populations, thereby advancing understanding of HIV persistence and informing cure strategies. Registration for the doctoral study will be with the University of KwaZulu-Natal.
Qualifications and experience:
The project will require the student to have an MSc or equivalent in virology, immunology, microbiology, biochemistry, bioinformatics or a related field. The ideal applicant will have experience of PCR, sequencing and sequence analysis, tissue culture and/or flow cytometry.
The following skills will be an advantage:

• Excellent written and oral communication skills.
• Ability to interact with persons of different cultures.
• Self-directed, meticulous, highly motivated, adaptable.
• Publications in peer-reviewed journals and conference presentations.

How to apply
Please complete an application form by clicking on the apply link above. You are expected to attach:

• A cover letter outlining your fit and research interests.
• One to two-page CV with publication list.
• Three academic references.
• Academic records.

Worker Type: Contingent Worker
The application closing date: 19 Dec 2025
Please note that only shortlisted candidates will be contacted, kindly consider your application as unsuccessful if you do not hear from us within 14 days of the application closing date.

Skills Required